RE-GEN™ is the first line of bioactive products to employ Bioglass as an active ingredient. Bioglass is backed by 50+ years of medical use, and is supported by scientific research and countless clinical studies. Bioglass has been proven to form a hydroxyapatite-like surface which promotes the regeneration of healthy tooth structure.
RE-GEN™ BIOACTIVE SUITE
Today there are various definitions of bioactivity and countless materials that claim to be bioactive, such as, Glass Ionomers, Resin Glass ionomers and Giomers. While these materials claim to have bioactive properties, there is extremely limited indications that they are able to stimulate the formation of hydroxyapatites.
RE-GEN™ brings clarity to all the uncertainty surrounding previous generations of bioactive dental materials. RE-GEN™ is the first line of bioactive products to employ Bioglass as an active ingredient. Bioglass is backed by 50+ years of medical use, and is supported by scientific research and countless clinical studies. Bioglass has been proven to form a hydroxyapatite-like surface which promotes the regeneration of healthy tooth structure.
Bioglass is also osteoinductive, i.e., it is able to stimulate bone cells towards a path of regeneration and self-repair, thus significantly accelerating tissue healing kinetics*. In vivo studies have shown that bioactive glasses bond with bone more rapidly than other bioceramics, and in vitro studies indicate that their osteogenic properties are due to their dissolution products stimulating osteoprogenitor cells at the genetic level*. Crystallization of the bone-like matrix and maturation of the bone cells are what lead to new bone formation.
Additionally, Bioglass releases alkaline species, which significantly increase the environment’s pH and provide broad antimicrobial effects*. These antimicrobial properties promote healing and prevention of caries.
All RE-GEN™ products are:
- BPA Free
* See Clinical Evidence for details.
THE RE-GEN™ SUITE OF BIOACTIVE PRODUCTS
PIT & FISSURE SEALANT
RE-GEN™ FLOWABLE COMPOSITE
Providing Unsurpassed Strength and Toughness
RE-GEN™ Flowable composite is formulated with a unique combination of thickness and flow in the same material. RE-GEN™ Flowable Composite provides unsurpassed strength and toughness while offering a high level of radiopacity. The use of Bioglass within this material promotes the regeneration of hydroxyapatite and provides antimicrobial function to prevent recurrent carries and secondary decay. These features improve the longevity and overall performance of the restoration.
- Releases calcium, phosphate, and fluoride to maximize the potential for remineralization of tooth structure
- Exceptional radiopacity < 300%
- Unsurpassed compressive strength of 357 MPa
- High modulus material provides a strong foundation within direct restorations
- Contains no Bisphenol A and no BPA derivatives
RE-GEN™ BIOACTIVE ADHESIVES
Don’t Let Your Bond Be A Barrier To Bioactivity
Bioactive materials, as they exist today, are inherently flawed. To properly place a composite restoration, an adhesive is placed on the tooth surface prior the delivery of the composite material. This adhesive layer does two things: bonds the composite to the tooth and SEALS the tooth from external elements. As the adhesive seals the tooth to prevent penetration of contaminants and bacteria, it also seals out any ion release from adjacent restorative materials. Since the adhesive acts as a barrier, preventing bioactive ions from the composite from reaching the tooth, those ions cannot lead to the regeneration of tooth structure.
RE-GEN™ solves this issue by incorporating the bioactive materials directly into the adhesive layer. Unlike traditional adhesives, RE-GEN™ is not a barrier to bioactivity, but rather a powerful agent that deposits biologically charged ions directly onto the tooth – exactly where they are needed in order to promote regeneration of tooth structure.
RE-GEN™ Bioactive Adhesives
RE-GEN™ PIT & FISSURE
Ensuring Exceptional Margin Stability
RE-GEN™ Pit & Fissure Sealant is a hydrophilic, wet bond material, that bonds remarkably well in a moist environment. Because of its bioactive properties, RE-GEN™ is able to prevent demineralization and inhibit secondary caries at the margin, ensuring exceptional margin stability.
- Releases biologically charged ions (phosphate, calcium, fluoride) which enhances enamel remineralization, increases enamel hardness, and stimulates hydroxyapatite formation
- Low solubility of 0.06%
- Film thickness of 20-25 microns
- BPA & Bis-GMA Free