RE-GEN™ Bioactive EndoPutty: Transforming Root Repair with Bioactive Innovation

August 20, 2025

In the world of endodontics, achieving a perfect seal and encouraging tissue regeneration are twin goals that often feel like competing priorities. But what if there were a single material that could reliably do both — and make your workflow quicker, cleaner, and more predictable? Enter RE-GEN Bioactive EndoPutty from VistaApex: a next-generation, bioactive bioceramic formulated for the full spectrum of root repair and pulp treatment.

What makes it different?

When selecting a root repair material, dentists look for several critical properties: sealing ability, setting time, bioactivity, biocompatibility, and ease of use. EndoPutty is engineered to deliver on all these fronts:

  • Bioceramic, bioactive composition. Made from calcium sodium phosphosilicate and calcium aluminate cement, EndoPutty interacts with the natural moisture in the tooth to set, not just in dry environments. This composition supports a high pH environment to discourage bacterial growth.
  • Ready-to-use consistency. No mixing. Delivered in a prefilled syringe. This simplifies handling, reduces waste, and helps avoid variations that can come with manual mixing.
  • Fast, reliable set. Under an hour in most conditions. That means less chair time, more predictable treatment scheduling, and better patient experience.
  • Wash-out resistance & radiopacity. Even in the presence of moisture, the putty stays where you put it, and its radiopaque properties allow for accurate radiographic verification.

Clinical applications: When & How to use RE-GEN

Here are the situations where EndoPutty shines:

  1. Root perforation repair – Accessing, cleaning, and sealing the perforation with a strong, durable putty that integrates well with surrounding tissue.
  2. Resorption (internal/external) – Another environment where moisture is present; knowing the material resists wash-out is key.
  3. Apexification — forming an apical barrier in immature teeth; the fast set helps reduce risk between appointments.
  4. Root-end filling (e.g. apical surgery) – tight seal, radiographic confirmation, and durability.
  5. Pulp capping (direct or indirect) – maintain vital pulp tissue using a bioactive, protective barrier; thickness and sealing are essential.

Tips for best results

  • Store EndoPutty properly (sealed syringes, controlled temperature) to prevent premature hardening.
  • Ensure control of bleeding / moisture in the defect site — while some moisture is needed for setting, excess fluid can wash out material pre-set.
  • Always verify placement radiographically.
  • For pulp capping, apply at least 1.5 mm thickness.
  • Restore over putty promptly after pulp capping to protect the site and optimize patient comfort.

Why your practice & patients benefit

  • More efficient procedures = more cases, less fatigue, better scheduling.
  • Strong biological response = fewer complications, less retreatment.
  • Predictable outcomes build trust with patients.
  • New technology helps your practice stand out as cutting edge.

Conclusion

RE-GEN Bioactive EndoPutty isn’t “just another root repair material” — it’s a bioactive, fast-setting, wash-resistant solution that helps solve many of the frustrations endodontists face when managing challenging cases. If you’re looking to streamline your workflow while enhancing biological outcomes, give EndoPutty a serious look.