
The power of Attraction, Creating Bio-Regenerative Restorations.
Reduce restorative failure & sensitivity. Construct longer lasting restorations.

World's #1 Bioglass Adhesive
Bio-Regenerative Exchange
Click on the image to the right to explore the continuous effects that Bioglass 45S5 has on the oral environment and resin dentin interface.

Developed with Dr. John Kanca.
RE-GEN™ is a ground up approach to Bioactivity. In addition to releasing ions, RE-GEN™ attracts ions from the oral environment, creating a continuous buffering and healing interface.
45S5Bioglass 45S5
RE-GEN™ is the first line of bioactive products to employ Bioglass 45S5 as an active ingredient. Backed by over 50 years of medical use, Bioglass is supported by countless clinical studies. Bioglass has been proven to promote bio-regenerative healing, while attracting and exchanging ions with the oral environment.
A Strong FoundationA Strong Foundation
RE-GEN™ Universal Adhesive and RE-GEN™ Flowable Composite Liner work together to form a bioactive foundation for a successful restoration by depositing fluoride, calcium and phosphate at the resin dentin interface.
Buffer is BetterBuffer is Better
Chemical demineralization of teeth is caused by acidic attack through two primary means: consumption of acidic food or drink and bacteria present in the mouth. At a low pH, hydroxyapatite is easily solubilized, and the tooth is at risk of erosion and secondary decay. RE-GEN™ has the ability to resist acidic attack by neutralizing these agents.

Universal Adhesive
Single Bottle Adhesive System

Flowable
Composite Liner

Self-Etch Adhesive
Results in highest bond strengths.

Pit & Fissure
Bio-Constructive Sealant

Clean & Boost
Dentin & Enamel Cleanser
Supporting Research
by UAB School of Dentistry, Dr. Chan Te Huang DDS, MS and Dr. Nathaniel Lawson DMD, PhD.
Testing Method:
Specimens are subjected to a demineralization, and remineralization process placed in acrylic blocks, and sectioned into 100 micron thick sections for examination under a polarized light microscope.
Materials were compared by their ability to prevent erosion and eliminate wall lesions.

Reference adhesive and composite
Non ion-releasing adhesive and composite leads to wall lesions and erosion. Resulting in compromised marginal integrity, sensitivity, and secondary decay.
Burgess Artificial Caries ModelBurgess Artificial Caries Model
- Box preparations are made on the buccal surface of human molar with margins in enamel and dentin . (10) Box preparations are filled with specified composite and restorative.
- Tooth specimens are embedded and sectioned.
- Each tooth stored in demineralized solutions for 4 hours and remineralization solution for 20 hours, cycled daily for 30 days.
RE-GEN™ Universal Adhesive + Flowable Composite Liner
No wall lesions, and a large zone of protection.
By utilizing the RE-GEN™ line of products and protocol, you’ll help prevent secondary decay, enjoy longer lasting restorations and less post-operative sensitivity; giving your restorations the best chance of long-lasting success
Are your materials protecting your restoration?
Why this matters...
It is no longer simply the goal of dentistry to relieve pain, restore missing oral cavity structures, and provide aesthetic results.
Incorporating bio-regenerative materials that work in conjunction with the healing ability of the human body will help revitalize teeth to extend the life of your restorations.
Ready to find out more?
Download the Research Summary Brochure today!
RE-GEN Technique
Utilizing an Open Sandwich Technique:
- For optimal results, use RE-GEN™ Universal Adhesive and RE-GEN™ Flowable Composite Liner utilizing an open technique.
- Co-Cure the materials together as a replacement to dentin, also filling the cervical part of the box.
- This results in exposure of 45S5 (BAG or Bio-Active Glass) to the oral environment, fueling RE-GEN™’s Bio-Regenerative impact and pH buffering.

Universal Adhesive
Single Bottle Adhesive System

Flowable
Composite Liner

Self-Etch Adhesive
Results in highest bond strengths.

Pit & Fissure
Bio-Constructive Sealant

Clean & Boost
Dentin & Enamel Cleanser